{"id":31691,"date":"2026-10-28T08:48:34","date_gmt":"2026-10-28T07:48:34","guid":{"rendered":"https:\/\/www.delc.ch\/medecin-prescripteur\/dermatologie-medecins-referents\/prurigo-nodulaire\/"},"modified":"2026-10-28T08:48:34","modified_gmt":"2026-10-28T07:48:34","slug":"prurigo-nodulaire","status":"publish","type":"page","link":"https:\/\/www.delc.ch\/fr\/medecin-prescripteur\/dermatologie-medecins-referents\/prurigo-nodulaire\/","title":{"rendered":"Prurigo nodulaire"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"31691\" class=\"elementor elementor-31691 elementor-29934\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b65be37 e-flex e-con-boxed e-con e-parent\" data-id=\"b65be37\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-1bd8f4f e-con-full e-flex e-con e-child\" data-id=\"1bd8f4f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1f7a5ee elementor-widget elementor-widget-text-editor\" data-id=\"1f7a5ee\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Prurigo nodulaire et autres formes de prurigo<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e1fe371 elementor-widget elementor-widget-image\" data-id=\"e1fe371\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"466\" src=\"https:\/\/www.delc.ch\/wp-content\/uploads\/2026\/09\/Prurigo-nodularis-1.jpg\" class=\"attachment-large size-large wp-image-31695\" alt=\"\" srcset=\"https:\/\/www.delc.ch\/wp-content\/uploads\/2026\/09\/Prurigo-nodularis-1.jpg 800w, https:\/\/www.delc.ch\/wp-content\/uploads\/2026\/09\/Prurigo-nodularis-1-300x175.jpg 300w, https:\/\/www.delc.ch\/wp-content\/uploads\/2026\/09\/Prurigo-nodularis-1-768x447.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-86bbe25 elementor-widget elementor-widget-text-editor\" data-id=\"86bbe25\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Les prurigos constituent un ensemble d\u2019affections cutan\u00e9es allant de l\u2019aigu au chronique, caract\u00e9ris\u00e9es par de fortes d\u00e9mangeaisons et par l\u2019apparition de papules, de nodules ou de traces de grattage plus ou moins marqu\u00e9es, accompagn\u00e9es de d\u00e9mangeaisons. Elles touchent principalement les adultes et ont soit des causes et des facteurs d\u00e9clenchants bien d\u00e9finis (par exemple, des piq\u00fbres d\u2019insectes ou des parasites tels que les puces, les poux, les acariens) ou sont souvent d\u2019origine multifactorielle (par exemple, les maladies atopiques, d\u2019autres affections cutan\u00e9es prurigineuses, les affections d\u2019origine m\u00e9dicamenteuse, infectieuse, psychosomatique ou neurologique ; les maladies syst\u00e9miques telles que les troubles h\u00e9patiques ou r\u00e9naux, les pathologies tumorales).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1638fcc e-flex e-con-boxed e-con e-parent\" data-id=\"1638fcc\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-eccad91 elementor-widget elementor-widget-n-accordion\" data-id=\"eccad91\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;all_collapsed&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2480\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2480\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Diagnostic et indication <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"icon icon-up-arrow1\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"icon icon-down-arrow1\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2480\" class=\"elementor-element elementor-element-3458ed4 e-con-full e-flex e-con e-child\" data-id=\"3458ed4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ce4789d elementor-widget elementor-widget-text-editor\" data-id=\"ce4789d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Cette affection se caract\u00e9rise par des l\u00e9sions cutan\u00e9es denses et nodulaires, aggrav\u00e9es par un grattage intense. Les nodules peuvent \u00eatre squameux, inflammatoires ou cro\u00fbteux et pr\u00e9senter des modifications kystiques.<\/p><p>Les facteurs de risque d&rsquo;apparition ou d&rsquo;aggravation de la maladie sont les d\u00e9mangeaisons chroniques, la dermatite atopique, le stress psychologique ainsi que la pr\u00e9sence de maladies syst\u00e9miques.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2481\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"2\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2481\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Signes cliniques et signes d'alerte <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"icon icon-up-arrow1\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"icon icon-down-arrow1\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2481\" class=\"elementor-element elementor-element-f4f24af e-con-full e-flex e-con e-child\" data-id=\"f4f24af\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-491ed56 elementor-widget elementor-widget-text-editor\" data-id=\"491ed56\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Des l\u00e9sions nodulaires accompagn\u00e9es de fortes d\u00e9mangeaisons apparaissent, associ\u00e9es \u00e0 une desquamation, \u00e0 la formation de cro\u00fbtes et \u00e0 une inflammation, qui s&rsquo;aggravent en cas de grattage r\u00e9p\u00e9t\u00e9.<\/p><p><strong>Signes d&rsquo;alerte<\/strong>: en cas d&rsquo;aggravation soudaine de l&rsquo;\u00e9tat cutan\u00e9, d&rsquo;apparition de douleurs ou de fi\u00e8vre, il convient d&rsquo;envisager une infection secondaire ou une affection grave. Le prurigo nodulaire peut \u00e9galement \u00eatre le signe d\u2019un diab\u00e8te, d\u2019une affection r\u00e9nale ou d\u2019une maladie bulleuse \u00e0 un stade pr\u00e9-clinique (par exemple, le pemphigo\u00efde bulleux). Par ailleurs, une an\u00e9mie ou une affection thyro\u00efdienne peuvent \u00e9galement \u00eatre envisag\u00e9es comme causes sous-jacentes. \u00c0 cet \u00e9gard, un examen m\u00e9dical est n\u00e9cessaire afin d\u2019exclure toute cause syst\u00e9mique.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2482\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"3\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2482\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Diagnostic et traitement <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"icon icon-up-arrow1\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"icon icon-down-arrow1\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2482\" class=\"elementor-element elementor-element-d4c93f0 e-con-full e-flex e-con e-child\" data-id=\"d4c93f0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bcfd7fe elementor-widget elementor-widget-text-editor\" data-id=\"bcfd7fe\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Le diagnostic est g\u00e9n\u00e9ralement pos\u00e9 sur la base des signes cliniques, ce qui n\u00e9cessite, le cas \u00e9ch\u00e9ant, d&rsquo;exclure toute maladie syst\u00e9mique. Le traitement topique repose sur l&rsquo;utilisation de corticost\u00e9ro\u00efdes ou d&rsquo;inhibiteurs de la calcineurine (par exemple, le tacrolimus). Si n\u00e9cessaire, un traitement syst\u00e9mique \u00e0 base d\u2019antihistaminiques oraux et d\u2019immunosuppresseurs (par exemple, le m\u00e9thotrexate) est mis en place. Pour les cas chroniques et r\u00e9fractaires au traitement, une phototh\u00e9rapie peut \u00eatre envisag\u00e9e. Dans les formes s\u00e9v\u00e8res, on recourt \u00e0 des m\u00e9dicaments biologiques tels que le dupilumab ou d\u2019autres anticorps monoclonaux. Les mesures g\u00e9n\u00e9rales comprennent la r\u00e9duction des d\u00e9mangeaisons, les soins cutan\u00e9s et le traitement des maladies sous-jacentes.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2483\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"4\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2483\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Valeur ajout\u00e9e pour le patient et le m\u00e9decin prescripteur <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"icon icon-up-arrow1\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"icon icon-down-arrow1\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2483\" class=\"elementor-element elementor-element-5f2672b e-con-full e-flex e-con e-child\" data-id=\"5f2672b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-70a9a38 elementor-widget elementor-widget-text-editor\" data-id=\"70a9a38\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Un traitement individualis\u00e9, conforme aux recommandations, permet non seulement de r\u00e9duire les d\u00e9mangeaisons et les l\u00e9sions cutan\u00e9es, mais aussi d\u2019am\u00e9liorer la qualit\u00e9 de vie des patients et de faciliter le suivi de leur \u00e9volution. Les m\u00e9decins prescripteurs b\u00e9n\u00e9ficient notamment d\u2019options th\u00e9rapeutiques claires dans les cas difficiles \u00e0 traiter, qui n\u00e9cessitent le recours \u00e0 des m\u00e9dicaments biologiques.<\/p><p>Il est toutefois important de souligner que le prurigo nodulaire peut \u00e9galement \u00eatre le signe de maladies syst\u00e9miques telles que le diab\u00e8te, les maladies r\u00e9nales ou les affections cutan\u00e9es v\u00e9siculaires (par exemple, le pemphigo\u00efde bulleux). C\u2019est pourquoi un bilan pr\u00e9coce et approfondi est essentiel pour identifier les causes sous-jacentes et mettre en place le traitement le plus adapt\u00e9.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2484\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"5\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2484\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Conclusion <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><i aria-hidden=\"true\" class=\"icon icon-up-arrow1\"><\/i><\/span>\n\t\t\t<span class='e-closed'><i aria-hidden=\"true\" class=\"icon icon-down-arrow1\"><\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2484\" class=\"elementor-element elementor-element-d46170d e-con-full e-flex e-con e-child\" data-id=\"d46170d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a203234 elementor-widget elementor-widget-text-editor\" data-id=\"a203234\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Le prurigo nodulaire n\u00e9cessite un traitement sur mesure et par \u00e9tapes. Les cas graves ou persistants doivent \u00eatre orient\u00e9s vers un service de dermatologie sp\u00e9cialis\u00e9 afin de b\u00e9n\u00e9ficier d&rsquo;options th\u00e9rapeutiques modernes, telles que les m\u00e9dicaments biologiques.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\n    <div class=\"xs_social_share_widget xs_share_url after_content \t\tmain_content  wslu-style-1 wslu-share-box-shaped wslu-fill-colored wslu-none wslu-share-horizontal wslu-theme-font-no wslu-main_content\">\n\n\t\t\n        <ul>\n\t\t\t        <\/ul>\n    <\/div> \n","protected":false},"excerpt":{"rendered":"<p>Prurigo nodulaire et autres formes de prurigo Les prurigos constituent un ensemble d\u2019affections cutan\u00e9es allant de l\u2019aigu au chronique, caract\u00e9ris\u00e9es par de fortes d\u00e9mangeaisons et par l\u2019apparition de papules, de nodules ou de traces de grattage plus ou moins marqu\u00e9es, accompagn\u00e9es de d\u00e9mangeaisons. Elles touchent principalement les adultes et ont soit des causes et des [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":31603,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"postBodyCss":"","postBodyMargin":[],"postBodyPadding":[],"postBodyBackground":{"backgroundType":"classic","gradient":""},"footnotes":""},"class_list":["post-31691","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Prurigo nodulaire - Clinique Delc<\/title>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Prurigo nodulaire - Clinique Delc\" \/>\n<meta property=\"og:description\" content=\"Prurigo nodulaire et autres formes de prurigo Les prurigos constituent un ensemble d\u2019affections cutan\u00e9es allant de l\u2019aigu au chronique, caract\u00e9ris\u00e9es par de fortes d\u00e9mangeaisons et par l\u2019apparition de papules, de nodules ou de traces de grattage plus ou moins marqu\u00e9es, accompagn\u00e9es de d\u00e9mangeaisons. 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